Cytochrome c oxidase subunit 5B, mitochondrial

BE0003989ProteinHumansCOX5B

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX5B
UniProtKB entry
P10606Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
129 residues · 13,696 Da
Also known as
Cytochrome c oxidase polypeptide Vb

Resolves to

Protein
UniProtP10606UniProt nameCOX5B_HUMAN
Gene
HGNCHGNC:2269NCBI Gene1329GeneCardsCOX5B
Pharmacology
KEGGhsa:1329
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cytochrome c oxidase subunit 5B, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In