Cytochrome c oxidase subunit 6C

BE0003990ProteinHumansCOX6C

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX6C
UniProtKB entry
P09669Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
75 residues · 8,781 Da
Also known as
Cytochrome c oxidase polypeptide VIc

Resolves to

Protein
UniProtP09669UniProt nameCOX6C_HUMAN
Gene
HGNCHGNC:2285NCBI Gene1345GenBank1200057GeneCardsCOX6C
Pharmacology
KEGGhsa:1345
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase subunit 6C, how selective are they, and which programs against it are still in active trials?

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