Cytochrome c oxidase subunit 7B, mitochondrial

BE0003991ProteinHumansCOX7B

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX7B
UniProtKB entry
P24311Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
80 residues · 9,160 Da
Also known as
Cytochrome c oxidase polypeptide VIIb

Resolves to

Protein
UniProtP24311UniProt nameCOX7B_HUMAN
Gene
HGNCHGNC:2291NCBI Gene1349GenBank30151GeneCardsCOX7B
Pharmacology
KEGGhsa:1349
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase subunit 7B, mitochondrial, how selective are they, and which programs against it are still in active trials?

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