Cytochrome c oxidase subunit 7C, mitochondrial

BE0003992ProteinHumansCOX7C

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX7C
UniProtKB entry
P15954Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
63 residues · 7,245 Da
Also known as
Cytochrome c oxidase polypeptide VIIc

Resolves to

Protein
UniProtP15954UniProt nameCOX7C_HUMAN
Gene
HGNCHGNC:2292NCBI Gene1350GenBank30155GeneCardsCOX7C
Pharmacology
KEGGhsa:1350
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase subunit 7C, mitochondrial, how selective are they, and which programs against it are still in active trials?

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