Cytochrome c oxidase subunit 6A2, mitochondrial

BE0003994ProteinHumansCOX6A2

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX6A2
UniProtKB entry
Q02221Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
97 residues · 10,815 Da
Also known as
COX VIa-M · COX6A · COX6AH · COXVIAH · Cytochrome c oxidase polypeptide VIa-heart

Resolves to

Protein
UniProtQ02221UniProt nameCX6A2_HUMAN
Gene
HGNCHGNC:2279NCBI Gene1339GenBank180946GeneCardsCOX6A2
Pharmacology
KEGGhsa:1339
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase subunit 6A2, mitochondrial, how selective are they, and which programs against it are still in active trials?

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