Cytochrome c oxidase subunit 6B1

BE0003995ProteinHumansCOX6B1

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. It is acted on by 2 drugs in DrugBank.

Gene name
COX6B1
UniProtKB entry
P14854Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
86 residues · 10,192 Da
Also known as
COX VIb-1 · COX6B · Cytochrome c oxidase subunit VIb isoform 1

Resolves to

Protein
UniProtP14854UniProt nameCX6B1_HUMAN
Gene
HGNCHGNC:2280NCBI Gene1340GenBank30295GeneCardsCOX6B1
Pharmacology
KEGGhsa:1340
Structure
PDB5Z62PDB9I6FPDB9I7U
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
14+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Cytochrome c oxidase subunit 6B1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In