Cytochrome c oxidase subunit 7A1, mitochondrial

BE0003996ProteinHumansCOX7A1

Component of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
COX7A1
UniProtKB entry
P24310Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
79 residues · 9,117 Da
Also known as
COX7AH · Cytochrome c oxidase subunit VIIa-H · Cytochrome c oxidase subunit VIIa-heart · Cytochrome c oxidase subunit VIIa-M · Cytochrome c oxidase subunit VIIa-muscle

Resolves to

Protein
UniProtP24310UniProt nameCX7A1_HUMAN
Gene
HGNCHGNC:2287NCBI Gene1346GenBank181405GeneCardsCOX7A1
Pharmacology
KEGGhsa:1346
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytochrome c oxidase subunit 7A1, mitochondrial, how selective are they, and which programs against it are still in active trials?

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