HLA class I histocompatibility antigen, B alpha chain

BE0004082ProteinHumansHLA-B

Antigen-presenting major histocompatibility complex class I (MHCI) molecule. It is acted on by 2 drugs in DrugBank.

Gene name
HLA-B
UniProtKB entry
P01889Swiss-Prot
Cellular location
Membrane
Residues / weight
362 residues · 40,428 Da
Also known as
HLA class I histocompatibility antigen, B-27 alpha chain · HLA-B · HLAB · Human leukocyte antigen B · MHC class I antigen B*27

Resolves to

Protein
UniProtP01889UniProt nameHLAB_HUMAN
Gene
HGNCHGNC:4932GenBank896271
Structure
PDB1HSAPDB1JGDPDB1JGE
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
15Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
26GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
24+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on HLA class I histocompatibility antigen, B alpha chain, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In