HTH-type transcriptional regulator TtgR

BE0004096ProteinPseudomonas putida (strain DOT-T1E)ttgR

Represses expression from the ttgABC operon promoter and its own expression. It is acted on by 4 drugs in DrugBank.

Gene name
ttgR
UniProtKB entry
Q9AIU0Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
210 residues · 23,854 Da
Also known as
Toluene efflux pump ttgABC operon repressor

Resolves to

Protein
UniProtQ9AIU0UniProt nameTTGR_PSEPT
Gene
GenBank13183097
Pharmacology
KEGGppx:T1E_0244
Structure
PDB2UXHPDB2UXIPDB2UXO
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on HTH-type transcriptional regulator TtgR, how selective are they, and which programs against it are still in active trials?

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