Aggrecan core protein

BE0004104ProteinHumansACAN

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. It is acted on by 1 drug in DrugBank.

Gene name
ACAN
UniProtKB entry
P16112Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
2,530 residues · 261,326 Da
Also known as
AGC1 · Cartilage-specific proteoglycan core protein · Chondroitin sulfate proteoglycan 1 · Chondroitin sulfate proteoglycan core protein 1 · CSPCP

Resolves to

Protein
UniProtP16112UniProt namePGCA_HUMAN
Gene
HGNCHGNC:319NCBI Gene176GenBank178259GeneCardsACAN
Pharmacology
KEGGhsa:176
Structure
PDB4MD4PDB7RDVPDB9DFF
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Aggrecan core protein, and which indications are they being tested in?

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