Ilomastat

DB02255ExperimentalSmall molecule

Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.

Chemical structure of Ilomastat
Mechanism
Curator reviewed
Formula / weight
C20H28N4O4 · 388.4607 g/mol (avg)
Also known as
(R)-N(SUP 1)-HYDROXY-N-((S)-2-INDOL-3-YL-1-(METHYLCARBAMOYL)ETHYL)-2-ISOBUTYLSUCCINAMIDE · (S-(R*,S*))-N(SUP 4)-HYDROXY-N(SUP 1)-(1H-INDOL-3-YLMETHYL)-2-(METHYLAMINO)-2-OXOETHYL)-2-(2-METHYLOPROPYL)BUTANEDIAMIDE
Code names
CS 610 · GM-6001

Resolves to

Compound
UNIII0403ML141CAS142880-36-2ChEMBLCHEMBL19611ChEBI137236PubChem132519KEGGD03793
Clinical / RWD
RxNorm1368877
Structure
InChIKeyNITYDPDXAAFEIT-DYVFJYSZSA-NSMILESCNC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC(C)C)CC(=O)NO
Targets
P15917lefP45452MMP13P39900MMP12P14780MMP9P08254MMP3P08253MMP2P22894MMP8P50281MMP14+3 more

What you can answer from here — as of September 23, 2026

11Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
32+ReferencesStructured and connected to the statements they support
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