Profilin-1

BE0004118ProteinHumansPFN1

Binds to actin and affects the structure of the cytoskeleton. It is acted on by 2 drugs in DrugBank.

Gene name
PFN1
UniProtKB entry
P07737Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
140 residues · 15,054 Da
Also known as
Epididymis tissue protein Li 184a · Profilin I

Resolves to

Protein
UniProtP07737UniProt namePROF1_HUMAN
Gene
HGNCHGNC:8881NCBI Gene5216GenBank190386GeneCardsPFN1
Pharmacology
KEGGhsa:5216
Structure
PDB1AWIPDB1CF0PDB1CJF
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Profilin-1, how selective are they, and which programs against it are still in active trials?

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