Geranyltranstransferase (Farnesyldiphosphate synthase)

BE0004143ProteinShigella flexneriispA

Geranyltranstransferase (Farnesyldiphosphate synthase) (Shigella flexneri) is a protein target in DrugBank. It is acted on by 1 drug in DrugBank.

Gene name
ispA
UniProtKB entry
A0A0H2UXE9TrEMBL
Residues / weight
299 residues · 32,142 Da
Also known as
Geranyltranstransferase,Farnesyl diphosphate synthase,geranyltranstransferase,Geranylgeranyl pyrophosphate synthase,heptaprenyl diphosphate synthase component II,Polyprenyl synthetase

Resolves to

Protein
UniProtA0A0H2UXE9UniProt nameA0A0H2UXE9_SHIFL
Gene
NCBI Gene1027686GenBank24050199
Pharmacology
KEGGsfl:SF0358
Structure
PDB2FOR
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Geranyltranstransferase (Farnesyldiphosphate synthase), and which indications are they being tested in?

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