Annexin A5

BE0004149ProteinHumansANXA5

This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. It is acted on by 10 drugs in DrugBank.

Gene name
ANXA5
UniProtKB entry
P08758Swiss-Prot
Residues / weight
320 residues · 35,936 Da
Also known as
Anchorin CII · Annexin V · Annexin-5 · ANX5 · Calphobindin I

Resolves to

Protein
UniProtP08758UniProt nameANXA5_HUMAN
Gene
HGNCHGNC:543NCBI Gene308GeneCardsANXA5
Pharmacology
KEGGhsa:308
Structure
PDB1ANWPDB1ANXPDB1AVH
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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44+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Annexin A5, how selective are they, and which programs against it are still in active trials?

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