This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Technetium Tc-99m is a radiopharmaceutical indicated in imaging tests.

Generic Name
Technetium Tc-99m
DrugBank Accession Number
DB14227
Background

Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 98.9063
Monoisotopic: 98.906254554
Chemical Formula
Tc
Synonyms
  • 99Tc
  • Tc 99
  • Technetium (99mTc)
  • Technetium (Tc 99m)
  • Technetium 99m
  • Technetium Tc 99m
  • Technetium-99
  • Technetium-99m
  • Technetium-99mTc
  • Technetium, isotope of mass 99
  • Technetium, Tc-99m
  • Technetium,Tc-99m

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous transition metal compounds
Sub Class
Not Available
Direct Parent
Homogeneous transition metal compounds
Alternative Parents
Not Available
Substituents
Homogeneous transition metal
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
6EW75241VU
CAS number
14133-76-7
InChI Key
GKLVYJBZJHMRIY-NJFSPNSNSA-N
InChI
InChI=1S/Tc/i1+2
IUPAC Name
(99Tc)technetium
SMILES
[99Tc]

References

General References
Not Available
ChemSpider
8045783
RxNav
90650
Wikipedia
Technetium-99m

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentPsoriatic Arthritis1
4CompletedTreatmentThyroid Associated Ophthalmopathy1
3TerminatedDiagnosticCancer of Bone1
3TerminatedDiagnosticPulmonary Embolism1
3TerminatedOtherLung Structure Determination1
2CompletedNot AvailableMetastatic Renal Cell Carcinoma ( mRCC)1
2CompletedNot AvailablePituitary Neoplasms1
2SuspendedDiagnosticSquamous Cell Carcinoma of the Head and Neck (SCCHN)1
1CompletedTreatmentCancer2
1TerminatedTreatmentEndometrial Cancer1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravenous250 mCi
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0 mg/mLALOGPS
logP-1.3ALOGPS
logP0ChemAxon
logS1.08ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at July 04, 2018 22:53 / Updated at May 14, 2021 01:06