Cell adhesion molecule CEACAM5

BE0004224ProteinHumansCEACAM5

Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). It is acted on by 11 drugs in DrugBank.

Gene name
CEACAM5
UniProtKB entry
P06731Swiss-Prot
Cellular location
Cell membrane
Residues / weight
702 residues · 76,795 Da
Also known as
Carcinoembryonic antigen · Carcinoembryonic antigen-related cell adhesion molecule 5 · CEA · CEA cell adhesion molecule 5 · Meconium antigen 100

Resolves to

Protein
UniProtP06731UniProt nameCEAM5_HUMAN
Gene
HGNCHGNC:1817NCBI Gene1048GenBank180223GeneCardsCEACAM5
Pharmacology
KEGGhsa:1048
Structure
PDB1E07PDB2QSQPDB2QST
Drugs

What you can answer from here — as of December 03, 2024

11DrugsApproved to experimental, with action, bond type and pharmacological action
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21Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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43+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Cell adhesion molecule CEACAM5, and which indications are they being tested in?

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