Poliovirus receptor

BE0004247ProteinHumansPVR

Mediates NK cell adhesion and triggers NK cell effector functions. It is acted on by 4 drugs in DrugBank.

Gene name
PVR
UniProtKB entry
P15151Swiss-Prot
Cellular location
Cell membrane
Residues / weight
417 residues · 45,302 Da
Also known as
NECL-5 · Nectin-like protein 5 · PVS

Resolves to

Protein
UniProtP15151UniProt namePVR_HUMAN
Gene
HGNCHGNC:9705NCBI Gene5817GenBank190205GeneCardsPVR
Pharmacology
KEGGhsa:5817
Structure
PDB1DGIPDB1NN8PDB3EPC
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Poliovirus receptor, and which indications are they being tested in?

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