The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. Strains of the virus are selected based on their... Strains of the virus are selected based on their reduced incidence of spreading to the central nervous system but still having the ability to mimic the immune response that occurs after infection with the wild...
- Mechanism
- Curator reviewed · 3 references
The polio vaccine allows for the encounter of the polio virus by the immune system to be less threatening while still allowing for the body to mount a humoral response for protection against any future exposure of the virus. For the OPV specifically, upon administration, the vaccine elicits a local immune response in the intestinal mucous membranes, a location at which the poliovirus multiplies. Antibodies produced locally then will inhibit multiplication of following infections of the wildtype poliovirus.
- Also known as
- OPV
- Code names
- Oral Polio Vaccine
Resolves to
What you can answer from here — as of July 10, 2026
Which drugs share a target with Oral Polio Vaccine, and which of those have an active Phase 3 trial?
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