Alkaline phosphatase, placental type

BE0004314ProteinHumansALPP

Alkaline phosphatase that can hydrolyze various phosphate compounds. It is acted on by 2 drugs in DrugBank.

Gene name
ALPP
UniProtKB entry
P05187Swiss-Prot
Cellular location
Cell membrane
Residues / weight
535 residues · 57,953 Da
Also known as
3.1.3.1 · Alkaline phosphatase Regan isozyme · Placental alkaline phosphatase 1 · PLAP · PLAP-1

Resolves to

Protein
UniProtP05187UniProt namePPB1_HUMAN
Gene
HGNCHGNC:439NCBI Gene250GenBank178474GeneCardsALPP
Pharmacology
KEGGhsa:250
Structure
PDB1EW2PDB1ZEBPDB1ZED
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alkaline phosphatase, placental type, how selective are they, and which programs against it are still in active trials?

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