Meiotic recombination protein DMC1 homolog

BE0004447ProteinHumansDMC1

Homologous DNA recombinase that catalyzes strand exchange during meiotic recombination (PubMed:15164066, PubMed:21307306, PubMed:26976601). It is acted on by 1 drug in DrugBank.

Gene name
DMC1
UniProtKB entry
Q14565Swiss-Prot
Cellular location
Chromosome
Residues / weight
340 residues · 37,681 Da
Also known as
3.6.4.- · DMC1H · LIM15

Resolves to

Protein
UniProtQ14565UniProt nameDMC1_HUMAN
Gene
HGNCHGNC:2927NCBI Gene11144GeneCardsDMC1
Pharmacology
KEGGhsa:11144
Structure
PDB1V5WPDB2ZJBPDB4HYY
Drugs

What you can answer from here — as of June 19, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Meiotic recombination protein DMC1 homolog, and which indications are they being tested in?

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