Phosphoglucomutase-1

BE0004461ProteinHumansPGM1

Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate (PubMed:15378030, PubMed:25288802). It is acted on by 3 drugs in DrugBank.

Gene name
PGM1
UniProtKB entry
P36871Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
562 residues · 61,449 Da
Also known as
5.4.2.2 · Glucose phosphomutase 1 · PGM 1

Resolves to

Protein
UniProtP36871UniProt namePGM1_HUMAN
Gene
HGNCHGNC:8905NCBI Gene5236GeneCardsPGM1
Pharmacology
KEGGhsa:5236
Structure
PDB5EPCPDB5F9CPDB5HSH
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
26+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Phosphoglucomutase-1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In