Vimentin

BE0004469ProteinHumansVIM

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. It is acted on by 4 drugs in DrugBank.

Gene name
VIM
UniProtKB entry
P08670Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
466 residues · 53,651 Da

Resolves to

Protein
UniProtP08670UniProt nameVIME_HUMAN
Gene
HGNCHGNC:12692NCBI Gene7431GeneCardsVIM
Pharmacology
KEGGhsa:7431
Structure
PDB1GK4PDB1GK6PDB1GK7
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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18GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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52+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vimentin, how selective are they, and which programs against it are still in active trials?

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