cAMP-dependent protein kinase catalytic subunit beta

BE0004475ProteinHumansPRKACB

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs (PubMed:12420224, PubMed:21423175, PubMed:31112131). It is acted on by 2 drugs in DrugBank.

Gene name
PRKACB
UniProtKB entry
P22694Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
351 residues · 40,622 Da
Also known as
2.7.11.11 · PKA C-beta

Resolves to

Protein
UniProtP22694UniProt nameKAPCB_HUMAN
Gene
HGNCHGNC:9381NCBI Gene5567GeneCardsPRKACB
Pharmacology
IUPHAR/GtoPdb1477KEGGhsa:5567
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
14GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
15+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on cAMP-dependent protein kinase catalytic subunit beta, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In