Ras-related protein Rab-7a

BE0004485ProteinHumansRAB7A

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. It is acted on by 1 drug in DrugBank.

Gene name
RAB7A
UniProtKB entry
P51149Swiss-Prot
Cellular location
Cytoplasmic vesicle, phagosome membrane
Residues / weight
207 residues · 23,490 Da
Also known as
3.6.5.2 · RAB7

Resolves to

Protein
UniProtP51149UniProt nameRAB7A_HUMAN
Gene
HGNCHGNC:9788NCBI Gene7879GeneCardsRAB7A
Pharmacology
KEGGhsa:7879
Structure
PDB1T91PDB1YHNPDB3LAW
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ras-related protein Rab-7a, and which indications are they being tested in?

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