DNA nucleotidylexotransferase

BE0004486ProteinHumansDNTT

Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. It is acted on by 2 drugs in DrugBank.

Gene name
DNTT
UniProtKB entry
P04053Swiss-Prot
Cellular location
Nucleus
Residues / weight
509 residues · 58,536 Da
Also known as
2.7.7.31 · TDT · Terminal addition enzyme · Terminal deoxynucleotidyltransferase · Terminal transferase

Resolves to

Protein
UniProtP04053UniProt nameTDT_HUMAN
Gene
HGNCHGNC:2983NCBI Gene1791GeneCardsDNTT
Pharmacology
KEGGhsa:1791
Structure
PDB2COEPDB5W4E
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA nucleotidylexotransferase, and which indications are they being tested in?

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