Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

BE0004519ProteinHumansMGAT1

Initiates complex N-linked carbohydrate formation. It is acted on by 1 drug in DrugBank.

Gene name
MGAT1
UniProtKB entry
P26572Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
445 residues · 50,878 Da
Also known as
2.4.1.101 · GGNT1 · GlcNAc-T I · GLCT1 · GLYT1

Resolves to

Protein
UniProtP26572UniProt nameMGAT1_HUMAN
Gene
HGNCHGNC:7044NCBI Gene4245GeneCardsMGAT1
Pharmacology
KEGGhsa:4245
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, and which indications are they being tested in?

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