Ras-related protein Rab-5A

BE0004533ProteinHumansRAB5A

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. It is acted on by 3 drugs in DrugBank.

Gene name
RAB5A
UniProtKB entry
P20339Swiss-Prot
Cellular location
Cell membrane
Residues / weight
215 residues · 23,659 Da
Also known as
3.6.5.2 · RAB5

Resolves to

Protein
UniProtP20339UniProt nameRAB5A_HUMAN
Gene
HGNCHGNC:9783NCBI Gene5868GeneCardsRAB5A
Pharmacology
KEGGhsa:5868
Structure
PDB1N6HPDB1N6IPDB1N6K
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ras-related protein Rab-5A, and which indications are they being tested in?

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