ADP-ribosylation factor-like protein 1

BE0004535ProteinHumansARL1

GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex (PubMed:21239483, PubMed:22679020, PubMed:27373159, PubMed:27436755, PubMed:9624189, PubMed:12972563). It is acted on by 1 drug in DrugBank.

Gene name
ARL1
UniProtKB entry
P40616Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
181 residues · 20,417 Da

Resolves to

Protein
UniProtP40616UniProt nameARL1_HUMAN
Gene
HGNCHGNC:692NCBI Gene400GeneCardsARL1
Pharmacology
KEGGhsa:400
Structure
PDB1UPTPDB4DCNPDB5EE5
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ADP-ribosylation factor-like protein 1, and which indications are they being tested in?

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