Glutathione S-transferase theta-2

BE0004541ProteinHumansGSTT2

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:1417752). It is acted on by 2 drugs in DrugBank.

Gene name
GSTT2
UniProtKB entry
P0CG29Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
244 residues · 27,506 Da
Also known as
2.5.1.18 · GST class-theta-2

Resolves to

Protein
UniProtP0CG29UniProt nameGST2_HUMAN
Gene
HGNCHGNC:4642NCBI Gene2953GeneCardsGSTT2
Pharmacology
KEGGhsa:2953
Structure
PDB4MPF
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase theta-2, how selective are they, and which programs against it are still in active trials?

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