SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

BE0004581ProteinHumansSMARCA5

ATPase that possesses intrinsic ATP-dependent nucleosome-remodeling activity (PubMed:12972596, PubMed:28801535). It is acted on by 2 drugs in DrugBank.

Gene name
SMARCA5
UniProtKB entry
O60264Swiss-Prot
Cellular location
Nucleus
Residues / weight
1,052 residues · 121,904 Da
Also known as
3.6.4.- · hSNF2H · SMARCA5 · SNF2H · Sucrose nonfermenting protein 2 homolog

Resolves to

Protein
UniProtO60264UniProt nameSMCA5_HUMAN
Gene
HGNCHGNC:11101NCBI Gene8467GeneCardsSMARCA5
Pharmacology
KEGGhsa:8467
Structure
PDB6NE3PDB8V4YPDB8V6V
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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28GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which compounds in development act on SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, and which indications are they being tested in?

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