Aurora kinase C

BE0004601ProteinHumansAURKC

Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. It is acted on by 13 drugs in DrugBank.

Gene name
AURKC
UniProtKB entry
Q9UQB9Swiss-Prot
Cellular location
Nucleus
Residues / weight
309 residues · 35,591 Da
Also known as
2.7.11.1 · AIE2 · AIK3 · AIRK3 · ARK-3

Resolves to

Protein
UniProtQ9UQB9UniProt nameAURKC_HUMAN
Gene
HGNCHGNC:11391NCBI Gene6795GeneCardsAURKC
Pharmacology
IUPHAR/GtoPdb1938KEGGhsa:6795
Structure
PDB6GR8PDB6GR9PDB9ESA
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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41+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aurora kinase C, how selective are they, and which programs against it are still in active trials?

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