Selenocysteine lyase

BE0004605ProteinHumansSCLY

Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. It is acted on by 2 drugs in DrugBank.

Gene name
SCLY
UniProtKB entry
Q96I15Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
445 residues · 48,148 Da
Also known as
4.4.1.16 · hSCL · SCL

Resolves to

Protein
UniProtQ96I15UniProt nameSCLY_HUMAN
Gene
HGNCHGNC:18161NCBI Gene51540GeneCardsSCLY
Pharmacology
KEGGhsa:51540
Structure
PDB3GZCPDB3GZD
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Selenocysteine lyase, how selective are they, and which programs against it are still in active trials?

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