N-acetylmuramoyl-L-alanine amidase

BE0004613ProteinHumansPGLYRP2

May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. It is acted on by 5 drugs in DrugBank.

Gene name
PGLYRP2
UniProtKB entry
Q96PD5Swiss-Prot
Cellular location
Secreted
Residues / weight
576 residues · 62,216 Da
Also known as
3.5.1.28 · Peptidoglycan recognition protein 2 · Peptidoglycan recognition protein long · PGLYRPL · PGRP-L

Resolves to

Protein
UniProtQ96PD5UniProt namePGRP2_HUMAN
Gene
HGNCHGNC:30013NCBI Gene114770GeneCardsPGLYRP2
Pharmacology
KEGGhsa:114770
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on N-acetylmuramoyl-L-alanine amidase, how selective are they, and which programs against it are still in active trials?

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