Alpha-N-acetylgalactosaminidase

BE0004619ProteinHumansNAGA

Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. It is acted on by 2 drugs in DrugBank.

Gene name
NAGA
UniProtKB entry
P17050Swiss-Prot
Cellular location
Lysosome
Residues / weight
411 residues · 46,564 Da
Also known as
3.2.1.49 · Alpha-galactosidase B

Resolves to

Protein
UniProtP17050UniProt nameNAGAB_HUMAN
Gene
HGNCHGNC:7631NCBI Gene4668GeneCardsNAGA
Pharmacology
KEGGhsa:4668
Structure
PDB3H53PDB3H54PDB3H55
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alpha-N-acetylgalactosaminidase, how selective are they, and which programs against it are still in active trials?

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