Small ribosomal subunit protein uS8

BE0004652ProteinEscherichia coli (strain K12)rpsH

One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit. It is acted on by 3 drugs in DrugBank.

Gene name
rpsH
UniProtKB entry
P0A7W7Swiss-Prot
Residues / weight
130 residues · 14,126 Da
Also known as
30S ribosomal protein S8

Resolves to

Protein
UniProtP0A7W7UniProt nameRS8_ECOLI
Gene
NCBI Gene947802
Pharmacology
KEGGecj:JW3268
Structure
PDB1EG0PDB1M5GPDB1S03
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Small ribosomal subunit protein uS8, how selective are they, and which programs against it are still in active trials?

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