Folic acid synthesis protein FOL1

BE0004658ProteinBaker's yeastFOL1

Catalyzes three sequential steps of tetrahydrofolate biosynthesis. It is acted on by 1 drug in DrugBank.

Gene name
FOL1
UniProtKB entry
P53848Swiss-Prot
Cellular location
Mitochondrion membrane
Residues / weight
824 residues · 93,119 Da
Also known as
4.1.2.25 · DHNA

Resolves to

Protein
UniProtP53848UniProt nameFOL1_YEAST
Gene
NCBI Gene855465
Pharmacology
KEGGsce:YNL256W
Structure
PDB2BMB
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Folic acid synthesis protein FOL1, how selective are they, and which programs against it are still in active trials?

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