Sulfacetamide is a sulfonamide used to treat inflammatory ocular conditions and acne vulgaris. An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
- Mechanism
- Curator reviewed
Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), an essential component for bacterial growth (according to the Woods-Fildes theory). The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
- Primary indication
- For the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis.Curator reviewed · 4 structured indications
- Formula / weight
- C8H10N2O3S · 214.242 g/mol (avg)
- First approval
- Canada, 2001 · United States, 1961
- Also known as
- Acetosulfamine · N-Acetylsulfanilamide · N-Sulfanilylacetamide · N-Sulphanilylacetamide · N'-acetylsulfanilamide
- Code names
- NSC-63871
- Brand names
Resolves to
Structure
InChIKey
SKIVFJLNDNKQPD-UHFFFAOYSA-NSMILESCC(=O)NS(=O)(=O)C1=CC=C(N)C=C1What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Sulfacetamide, and which of those have an active Phase 3 trial?
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