Keratin, type I cytoskeletal 12

BE0004660ProteinHumansKRT12

Structural component of intermediate filaments in the corneal epithelium. It is acted on by 2 drugs in DrugBank.

Gene name
KRT12
UniProtKB entry
Q99456Swiss-Prot
Residues / weight
494 residues · 53,511 Da
Also known as
CK-12 · Cytokeratin-12 · K12 · Keratin-12

Resolves to

Protein
UniProtQ99456UniProt nameK1C12_HUMAN
Gene
HGNCHGNC:6414NCBI Gene3859GeneCardsKRT12
Pharmacology
KEGGhsa:3859
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Keratin, type I cytoskeletal 12, how selective are they, and which programs against it are still in active trials?

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