Diamine oxidase [copper-containing]

BE0004667ProteinPigAOC1

Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:1457410, PubMed:8144586). It is acted on by 1 drug in DrugBank.

Gene name
AOC1
UniProtKB entry
Q9TRC7Swiss-Prot
Cellular location
Secreted
Residues / weight
755 residues · 85,474 Da
Also known as
1.4.3.22 · ABP · ABP1 · Amiloride-binding protein · Amiloride-binding protein 1

Resolves to

Protein
UniProtQ9TRC7UniProt nameAOC1_PIG
Gene
NCBI Gene100517436
Pharmacology
KEGGssc:100517436
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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23GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Diamine oxidase [copper-containing], how selective are they, and which programs against it are still in active trials?

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