Lanosterol synthase

BE0004668ProteinYeastERG7

Lanosterol synthase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (PubMed:2185141, PubMed:8486282). It is acted on by 1 drug in DrugBank.

Gene name
ERG7
UniProtKB entry
Q04782Swiss-Prot
Residues / weight
728 residues · 83,714 Da
Also known as
2,3-epoxysqualene--lanosterol cyclase · 5.4.99.7 · Ergosterol biosynthesis protein 7 · OSC · Oxidosqualene--lanosterol cyclase

Resolves to

Protein
UniProtQ04782UniProt nameERG7_CANAL
Gene
NCBI Gene3635761
Pharmacology
KEGGcal:CaO19.1570
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lanosterol synthase, how selective are they, and which programs against it are still in active trials?

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