Sodium-driven chloride bicarbonate exchanger

BE0004683ProteinHumansSLC4A10

Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH (PubMed:18319254). It is acted on by 1 drug in DrugBank.

Gene name
SLC4A10
UniProtKB entry
Q6U841Swiss-Prot
Cellular location
Basolateral cell membrane
Residues / weight
1,118 residues · 125,945 Da
Also known as
NBCN2 · NCBE · Solute carrier family 4 member 10

Resolves to

Protein
UniProtQ6U841UniProt nameS4A10_HUMAN
Gene
HGNCHGNC:13811NCBI Gene57282GeneCardsSLC4A10
Pharmacology
KEGGhsa:57282
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
15GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Sodium-driven chloride bicarbonate exchanger, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In