Deoxycytidylate deaminase

BE0004700ProteinHumansDCTD

Catalyzes the deamination of dCMP to dUMP, providing the nucleoside monophosphate substrate for the thymidylate synthase/TYMS (PubMed:7685356). It is acted on by 1 drug in DrugBank.

Gene name
DCTD
UniProtKB entry
P32321Swiss-Prot
Residues / weight
178 residues · 20,016 Da
Also known as
3.5.4.12 · dCMP deaminase

Resolves to

Protein
UniProtP32321UniProt nameDCTD_HUMAN
Gene
HGNCHGNC:2710NCBI Gene1635GeneCardsDCTD
Pharmacology
KEGGhsa:1635
Structure
PDB2W4L
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
2Metabolic reactionsDrug transformations it catalyses, substrate to product
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Deoxycytidylate deaminase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In