Asc-type amino acid transporter 1

BE0004709ProteinHumansSLC7A10

Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. It is acted on by 1 drug in DrugBank.

Gene name
SLC7A10
UniProtKB entry
Q9NS82Swiss-Prot
Cellular location
Cell membrane
Residues / weight
523 residues · 56,797 Da
Also known as
Asc-1 · ASC1 · Solute carrier family 7 member 10

Resolves to

Protein
UniProtQ9NS82UniProt nameAAA1_HUMAN
Gene
HGNCHGNC:11058NCBI Gene56301GeneCardsSLC7A10
Pharmacology
KEGGhsa:56301
Structure
PDB8QEYPDB8WNSPDB8WNT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Asc-type amino acid transporter 1, how selective are they, and which programs against it are still in active trials?

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