Breakpoint cluster region protein

BE0004743ProteinHumansBCR

Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. It is acted on by 4 drugs in DrugBank.

Gene name
BCR
UniProtKB entry
P11274Swiss-Prot
Cellular location
Postsynaptic density
Residues / weight
1,271 residues · 142,818 Da
Also known as
2.7.11.1 · BCR1 · D22S11 · Renal carcinoma antigen NY-REN-26

Resolves to

Protein
UniProtP11274UniProt nameBCR_HUMAN
Gene
HGNCHGNC:1014NCBI Gene613GeneCardsBCR
Pharmacology
KEGGhsa:613
Structure
PDB1K1FPDB2AINPDB5N6R
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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104Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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40+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Breakpoint cluster region protein, how selective are they, and which programs against it are still in active trials?

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