Serine/threonine-protein kinase Nek11

BE0004758ProteinHumansNEK11

Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. It is acted on by 2 drugs in DrugBank.

Gene name
NEK11
UniProtKB entry
Q8NG66Swiss-Prot
Cellular location
Nucleus
Residues / weight
645 residues · 74,192 Da
Also known as
2.7.11.1 · Never in mitosis A-related kinase 11 · NimA-related protein kinase 11

Resolves to

Protein
UniProtQ8NG66UniProt nameNEK11_HUMAN
Gene
HGNCHGNC:18593NCBI Gene79858GeneCardsNEK11
Pharmacology
IUPHAR/GtoPdb2116KEGGhsa:79858
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase Nek11, how selective are they, and which programs against it are still in active trials?

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