Sodium- and chloride-dependent GABA transporter 2

BE0004776ProteinHumansSLC6A13

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:17502375, PubMed:22932902). It is acted on by 1 drug in DrugBank.

Gene name
SLC6A13
UniProtKB entry
Q9NSD5Swiss-Prot
Cellular location
Cell membrane
Residues / weight
602 residues · 68,008 Da
Also known as
GAT-2 · GAT2 · Solute carrier family 6 member 13

Resolves to

Protein
UniProtQ9NSD5UniProt nameS6A13_HUMAN
Gene
HGNCHGNC:11046NCBI Gene6540GeneCardsSLC6A13
Pharmacology
KEGGhsa:6540
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sodium- and chloride-dependent GABA transporter 2, and which indications are they being tested in?

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