Complement component 1 Q subcomponent-binding protein, mitochondrial

BE0004930ProteinHumansC1QBP

Multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, protein synthesis in mitochondria, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing (PubMed:10022843, PubMed:10479529, PubMed:10722602, PubMed:11086025, PubMed:11859136, PubMed:15243141, PubMed:16140380, PubMed:16177118, PubMed:17881511, PubMed:18676636, PubMed:19004836,... It is acted on by 2 drugs in DrugBank.

Gene name
C1QBP
UniProtKB entry
Q07021Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
282 residues · 31,362 Da
Also known as
ASF/SF2-associated protein p32 · C1qBP · gC1q-R protein · GC1QBP · Glycoprotein gC1qBP

Resolves to

Protein
UniProtQ07021UniProt nameC1QBP_HUMAN
Gene
HGNCHGNC:1243NCBI Gene708GeneCardsC1QBP
Pharmacology
KEGGhsa:708
Structure
PDB1P32PDB3RPXPDB6SZW
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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52+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Complement component 1 Q subcomponent-binding protein, mitochondrial, how selective are they, and which programs against it are still in active trials?

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