Interphotoreceptor matrix proteoglycan 2

BE0004942ProteinHumansIMPG2

Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. It is acted on by 1 drug in DrugBank.

Gene name
IMPG2
UniProtKB entry
Q9BZV3Swiss-Prot
Cellular location
Photoreceptor outer segment membrane
Residues / weight
1,241 residues · 138,619 Da
Also known as
Interphotoreceptor matrix proteoglycan of 200 kDa · IPM 200 · IPM200 · Sialoprotein associated with cones and rods proteoglycan · Spacrcan

Resolves to

Protein
UniProtQ9BZV3UniProt nameIMPG2_HUMAN
Gene
HGNCHGNC:18362NCBI Gene50939GeneCardsIMPG2
Pharmacology
KEGGhsa:50939
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interphotoreceptor matrix proteoglycan 2, how selective are they, and which programs against it are still in active trials?

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