Intracellular hyaluronan-binding protein 4

BE0004943ProteinHumansHABP4

Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). It is acted on by 1 drug in DrugBank.

Gene name
HABP4
UniProtKB entry
Q5JVS0Swiss-Prot
Cellular location
Nucleus
Residues / weight
413 residues · 45,785 Da
Also known as
Hyaluronan-binding protein 4 · IHABP-4 · IHABP4 · Ki-1/57 intracellular antigen

Resolves to

Protein
UniProtQ5JVS0UniProt nameHABP4_HUMAN
Gene
HGNCHGNC:17062NCBI Gene22927GeneCardsHABP4
Pharmacology
KEGGhsa:22927
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Intracellular hyaluronan-binding protein 4, how selective are they, and which programs against it are still in active trials?

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