Stabilin-2

BE0004948ProteinHumansSTAB2

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. It is acted on by 1 drug in DrugBank.

Gene name
STAB2
UniProtKB entry
Q8WWQ8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
2,551 residues · 276,986 Da
Also known as
FAS1 EGF-like and X-link domain-containing adhesion molecule 2 · Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2 · FEEL-2 · FEEL2 · FELL

Resolves to

Protein
UniProtQ8WWQ8UniProt nameSTAB2_HUMAN
Gene
HGNCHGNC:18629NCBI Gene55576GeneCardsSTAB2
Pharmacology
KEGGhsa:55576
Structure
PDB5N86
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Stabilin-2, how selective are they, and which programs against it are still in active trials?

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